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Environmental Health & Safety


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Incompatible Chemicals

The following are common examples of incompatible combinations:


Keep out of contact with:

Acetic Acid

perchloric acid, nitric acid, chromic acid, hydroxyl compounds, peroxides, permanganates, glycols


chlorine, bromine, copper, fluorine, silver, mercury

Alkali Metals (e.g. Sodium)

water, chlorinated hydrocarbons, carbon dioxide, halogens

Ammonia, Anhydrous

mercury, chlorine, calcium hypochlorite, iodine, bromine, hydrofluoric acid

Ammonium Nitrate

acids, metal powders, flammable liquids, chlorates, nitrites, sulfur, finely divided combustible materials


nitric acid, hydrogen peroxide


same as chlorine

Carbon, Activated

calcium hypochlorite, all oxidizing agents


ammonium salts, acids, metal powders, sulfur, finely divided combustible materials

Chromic Acid

acetic acid, naphthalene, camphor, glycerin, turpentine, alcohol, flammable liquids


ammonia, acetylene, butadiene, butane, methane, propane (or other petroleum gases), hydrogen, sodium carbide, turpentine, benzene, finely divided metals


acetylene, hydrogen peroxide

Flammable Liquids

ammonium nitrate, inorganic acids, hydrogen peroxide, sodium peroxide, halogens, chromic acid


fluorine, chlorine, bromine, chromic acid, sodium peroxide

Hydrofluoric Acid

anhydrous ammonia, ammonium hydroxide

Hydrogen Peroxide

copper, chromium, iron, most metals or their salts, alcohol, acetone, aniline, nitromethane, flammable liquids, oxidizing gases

Hydrogen Sulfide

fuming nitric acid, oxidizing gases


acetylene, ammonia (aqueous or anhydrous), hydrogen


acetylene, fulminic acid, ammonia

Nitric Acid

acetic acid, aniline, chromic acid, hydrocyanic acid, hydrogen sulfide, flammable liquids, flammable gases

Oxalic Acid

silver, mercury

Perchloric Acid

acetic anhydride, bismuth and its alloys, organic materials


carbon tetrachloride, carbon dioxide, water

Potassium Chlorate

sulfuric and other acids

Potassium Permanganate

glycerin, ethylene glycol, benzaldehyde, sulfuric acid


acetylene, oxalic acid, tartaric acid, ammonia compounds

Sodium Peroxide

alcohol, glacial acetic acid, acetic anhydride, benzaldehyde, carbon disulfide, glycerin, ethylene, glycol, ethyl acetate, methyl acetate, furfural

Sulfuric Acid

potassium chlorate, potassium perchlorate, potassium permanganate (or compounds with similar light metals, such as sodium, lithium, etc.)

Consult the SDS and chemical labels for the chemicals in your location for additional information on incompatible chemicals.

QUESTIONS or COMMENTS? Contact EH&S at (585) 275-3241 or e-mail EH&S at

This page last updated 7/30/2015. Disclaimer.